The following properties in Orangeburg County have been listed in the National Register as historic sites or districts.  From each site is a link to the original nomination in Adobe PDF format.

Note: most National Register properties are privately owned and are not open to the public. The privacy of owners should be respected.  Not all properties retain the same integrity as when originally documented and listed in the National Register due to changes and modifications over time.

• Alan Mack Site
• All Star Bowling Lane
• Amelia Street Historic District
• F. H. W. Briggman House
• Donald Bruce House
• Cattle Creek Campground
• Claflin College Historic District
• Cope Depot
• Dantzler Plantation
• Dixie Library Building
• Dukes Gymnasium
• East Russell Street Area Historic District
• Ellis Avenue Historic District
• Enterprise Cotton Mills Building
• Eutaw Springs Battleground Park
• Great Branch Teacherage
• Maj. John Hammond Fordham House
• Hodge Hall
• Hotel Eutaw
• Lowman Hall, South Carolina State College
• Mt. Pisgah Baptist Church
• Numertia Plantation
• Orangeburg City Cemetery
• Orangeburg County Fair Main Exhibit Building
• Orangeburg County Jail
• Orangeburg Downtown Historic District
• Providence Methodist Church
• South Carolina State College Historic District
• Southern Railway Passenger Depot
• Springfield High School
• St. Julien Plantation
• William P. Stroman House
• Tingley Memorial Hall, Claflin College
• Treadwell Street Historic District
• Trinity Lutheran Church
• Trinity Methodist Episcopal Church
• White House United Methodist Church
• Whitman Street Area Historic District
• Williams Chapel A.M.E. Church
• Willow Consolidated High School