Smith Building 2-6 S. Main St.	Hill Building 10 S. Main St.	Coggeshall Building 14-16 S. Main St.	Coggeshall Building 107-109 Orange St.	McLellan's Dept. Store 20 S. Main St.
Wolfram Building 24-26 S. Main St.	Jewel's Deluxe Cafe 32 S. Main St.	Coleman Building 38 S. Main St.	Manne Buildling 111-117 Pearl St.	103 Pearl St.
101 Pearl St.	42 and 44 Public Square	46 Public Square	48 Public Square	Willcox Building 50 Public Square
"The Darlington News" Building 101-103 Exchange St.	Bank of Darlington 54 E. Public Square

The Darlington Downtown Historic District is significant for its high level of architectural integrity and as an illustration of the significant periods of prosperity and building in Darlington. The district includes a collection of twenty-one contributing, intact commercial buildings associated with the growth of Darlington from ca. 1870 to ca. 1935. While significant periods of building and rebuilding are associated with the series of fires that swept through the city in 1866, 1892, and the 1930s, the buildings in this district also show the rise and fall of the city’s economy, especially as it relates to the production and sale of cotton and tobacco. The one, two, and three-part commercial buildings exhibit typical turn-of-the-twentieth century building styles, with brick detailing and, in some cases, cast-iron storefronts. By 1870, Darlington County led the state in cotton production. The 1880s and 1890s saw a period of great growth for the Darlington area that included the opening of several local industries including a cotton mill and a cotton compress company. In the early twentieth century the economy shifted to tobacco, and the town of Darlington became one of the state's largest tobacco markets. In the 1920s, overproduction and competition from international markets caused cotton and tobacco prices to drop, and the 1930s brought the Great Depression. Listed in the National Register July 5, 2006.

View a map showing the boundaries of the Darlington Downtown Historic District.